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Major responsibility:
- Perform hand-on sample preparation for the analysis of selected in vivo and in vitro assay samples (particularly for protein or ADC qualitative and quantitative assays) using LC-HRMS and LC-Triple Quad MS/MS to support discovery programs.
- Perform hand-on sample analysis to profile in-house and competitor compounds including small molecule and large molecule compounds.
- Perform hand-on sample analysis for project specific biomarkers.
- Perform method development and qualification to ensure successful method transfer to CROs for bioanalysis-related activities.
- Perform data analysis and compile method development and sample analysis results. Write study report as needed.
- Conduct hand-on troubleshooting for bioanalytical issues.
Other duties as assigned
Qualification and Experience
An individual with bachelor or master degree in life science with 0-5 years of working experience.
● Hand-on experience of bio-sample preparation including plasma, serum, cerebrospinal fluid and tissues. Working experience with regulatory bioanalysis is a plus.
● Training and/or experience with LC-MS/MS is required. Working experience with high resolution mass spectrometry (HRMS), e.g. Thermo Fisher Scientific Orbitrap, is preferred.
● Comfortable to work in a bilingual (English and Chinese) work environment.
● Strong organizational, communicational skills and ability to multi-tasking.
● Self-motivated and engaged learner.
Experience and knowledge of GxP and regulatory guidance are optional.