Principle Roles & Responsibilities /Accountabilities 主要職責(zé)/責(zé)任 - Perform hand-on sample preparation for the analysis of selected in vivo and in vitro assay samples (particularly for protein or ADC qualitative and quantitative assays) using LC-HRMS and LC-Triple Quad MS/MS to support discovery programs. - Perform hand-on sample analysis to profile in-house and competitor compounds including small molecule and large molecule compounds. - Perform hand-on sample analysis for project specific biomarkers. - Perform method development and qualification to ensure successful method transfer to CROs for bioanalysis-related activities. - Perform data analysis and compile method development and sample analysis results. Write study report as needed. - Conduct hand-on troubleshooting for bioanalytical issues. Other duties as assigned
Education/Qualifications教育程度/所獲資格證書
● An individual with bachelor or master degree in life science with 0-5 years of working experience.
Key Skill / Knowledge Requirements
● Hand-on experience of bio-sample preparation including plasma, serum, cerebrospinal fluid and tissues. Working experience with regulatory bioanalysis is a plus. ● Training and/or experience with LC-MS/MS is required. Working experience with high resolution mass spectrometry (HRMS), e.g. Thermo Fisher Scientific Orbitrap, is preferred. ● Comfortable to work in a bilingual (English and Chinese) work environment. ● Strong organizational, communicational skills and ability to multi-tasking. ● Self-motivated and engaged learner. ● Experience and knowledge of GxP and regulatory guidance are optional.